Arsenal make one change to the team that won at Southampton during the week. Gabriel Martinelli comes in for the absent Bukayo Saka. Kieran Tierney and Pierre-Emerick Aubameyang are both still out, but new loan signing Martin Odegaard might get on a bit later: he’s on the bench.

Manchester United replace nearly half of their starting XI after losing so dismally at home to Sheffield United. Anthony Martial, Axel Tuanzebe, Alex Telles, Nemanja Matic and Mason Greenwood make way for Edinson Cavani, Victor Lindelof, Luke Shaw, Scott McTominay and Fred.

Arsenal: Leno, Bellerin, Holding, Luiz, Cedric, Thomas, Xhaka, Martinelli, Smith-Rowe, Pepe, Lacazette.
Subs: Gabriel, Odegaard, Willian, Runarsson, Maitland-Niles, Chambers, Elneny, Willock, Nketiah.

Manchester United: de Gea, Wan Bissaka, Lindelof, Maguire, Shaw, McTominay, Fred, Rashford, Bruno Fernandes, Pogba, Cavani.
Subs: Bailly, Martial, Greenwood, James, Henderson, Alex Telles, Matic, van de Beek, Tuanzebe.

Manchester United haven’t beaten Arsenal in the league since April 2018, when Marouane Fellaini scored a last-minute winner at Old Trafford. They’ve lost 2-0 on their last two visits to the Emirates, and lost this season’s corresponding home fixture 1-0 back in November. Arsenal have picked up 16 points from the last 18 on offer, while United went down flaccidly against bottom side Sheffield United the other day. Form slightly favours the Gunners, then, but when was form a factor in an epic rivalry that has delivered brilliance, bench-emptying brawls, and everything in between? Let the duel commence, this could be a whole lot of fun.

Kick off is at 5.30pm GMT. It’s on!

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